Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 15/20 | 0.78 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.64 |
| ▸ | HTR3B | O95264 | 1/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.64 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.64 |
| ▸ | BCL6 | P41182 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968948 | 0.88 | ROCK1 (1.00) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL12813344 | 0.86 | ROCK1 (0.97) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15831241 | 0.86 | ROCK1 (1.00) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11685681 | 0.86 | ROCK1 (0.57) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11173594 | 0.82 | CA12 (0.58) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30565226 | 0.80 | ROCK1 (0.64) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL12813346 | 0.79 | ROCK1 (1.00) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27612768 | 0.79 | SYK (0.70) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11168680 | 0.79 | ALDH1A1 (0.50) | ROCK1TNNI3K | |
| SCHEMBL11170874 | 0.78 | TNNI3K (0.51) | ROCK1TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370431-A | Process for coloring fibre forming polyamides in the melt with azo pigments | CIBA-GEIGY CORPORATION (US) | 1983-01-25 | — | — | US | disclosed |