Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 6/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458402 | 0.83 | JAK2 (0.56) | JAK2JAK3MEN1KMT2AATM | |
| SCHEMBL29025269 | 0.81 | KMT2A (0.55) | JAK2JAK3MEN1KMT2AATM | |
| SCHEMBL30023094 | 0.80 | KMT2A (0.65) | JAK2JAK3MEN1KMT2AATM | |
| SCHEMBL11178043 | 0.80 | ROCK1 (0.78) | ROCK1JAK2JAK3HTR3EHTR3B | |
| SCHEMBL12968948 | 0.79 | ROCK1 (1.00) | ROCK1JAK2JAK3HTR3EHTR3B | |
| SCHEMBL4377112 | 0.78 | CDK1 (0.61) | JAK2JAK3 | |
| SCHEMBL15831241 | 0.78 | ROCK1 (1.00) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL12813344 | 0.78 | ROCK1 (0.97) | ROCK1JAK2JAK3HTR3EHTR3B | |
| SCHEMBL411428 | 0.77 | KCNA5 (0.51) | MEN1KMT2AATMPOLBPKM | |
| SCHEMBL14024354 | 0.77 | JAK3 (0.57) | JAK2JAK3MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486348-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | Trustlife Global Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-118804751-A | New compounds and treatment of renal cell carcinoma | 巴什生物技术公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2023166153-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | BASH BIOTECH INC (US) | 2023-09-07 | — | — | WO | disclosed |