SCHEMBL1117829

SCHEMBL1117829

C/C=C\[N+](=O)[O-]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420901 1.00
SCHEMBL420900 1.00
Bicarbonate SCHEMBL4299701 0.88 FBP1 (0.38)
Ethylene Glycol SCHEMBL23721619 0.86 ALDH1A1 (0.38)
SCHEMBL10528655 0.84 FBP1 (0.30)
SCHEMBL10909800 0.78
SCHEMBL13214996 0.78
SCHEMBL10909794 0.78
SCHEMBL2701677 0.76
SCHEMBL5957000 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111757758-A Ultrasonic contrast agent based on bilirubin derivative for diagnosis and treatment 株式会社毕丽斯 2020-10-09 CN claimed
CN-111182926-A Particles comprising bilirubin derivatives and metals 株式会社毕丽斯 2020-05-19 CN claimed
US-4506098-A Process for the preparation of 2,6-dialkylaniline from 1-nitroalkene CHEVRON RESEARCH COMPANY (US) 1985-03-19 US claimed
EP-3897833-B1 INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMA (US) 2026-02-04 EP disclosed
WO-2025087274-A1 AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE 浙江海正药业股份有限公司 2025-05-01 WO disclosed
US-20250042878-A1 INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMA (US) 2025-02-06 US disclosed
WO-2024245193-A1 HETEROAROMATIC RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 上海艾力斯医药科技股份有限公司 2024-12-05 WO disclosed
WO-2024245443-A1 COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-12-05 WO disclosed
US-12060346-B2 Inhibitors of APOL1 and methods of using same VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-08-13 US disclosed
WO-2024120415-A1 COMPOUNDS TARGETING SSTR2, PREPARATION METHOD THEREFOR, AND USE THEREOF 烟台蓝纳成生物技术有限公司 2024-06-13 WO disclosed
WO-2024109660-A1 CDK INHIBITORS 上海齐鲁制药研究中心有限公司 2024-05-30 WO disclosed
US-4088645-A O,O-Dialkylphosphoryloxy-2,3,5,8-tetrahydro-1H-s-triazolo[1,2a]pyridazine-1,3-diones HOFFMANN-LA ROCHE INC. (US) 1978-05-09 US disclosed
US-4087488-A Cyano-4-(0,0-dialkylphosphoryloxy)-cyclohex-4-enes HOFFMAN-LA ROCHE INC. (US) 1978-05-02 US disclosed
US-4077985-A 4-(O,O-Diester phosphoryloxy)cyclohex-4-en-1,2-carboxylic anhydrides HOFFMANN-LA ROCHE INC. (US) 1978-03-07 US disclosed
US-4025584-A 1-Acetyl-3(4)-(dihydrocarbylphosphoryloxy)-cyclohex-3-enes HOFFMANN-LA ROCHE INC. (US) 1977-05-24 US disclosed
US-4011239-A MANGANESE, VANADIUM, CERIUM MOBIL OIL CORPORATION (US) 1977-03-08 US disclosed
US-3978171-A PROCESS FOR THE PREPARATION OF DIENYLPHOSPHATES HOFFMANN-LA ROCHE INC. (US) 1976-08-31 US disclosed
US-3978172-A PROCESS FOR THE PREPARATION OF DIENYLPHOSPHATES HOFFMANN-LA ROCHE INC. (US) 1976-08-31 US disclosed
US-3972901-A Diels-Alder type process involving a geminal-dihalocyclopropane and a dienophile ETHYL CORPORATION (US) 1976-08-03 US disclosed
US-3933948-A Dienylphosphates HOFFMANN-LA ROCHE INC. (US) 1976-01-20 US disclosed