Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191579 | 0.98 | ACHE (0.55) | ACHECYP2D6MBTD1L3MBTL3ADRB1 | |
| SCHEMBL11189977 | 0.98 | ACHE (0.55) | ACHECYP2D6MBTD1L3MBTL3ADRB1 | |
| SCHEMBL14701580 | 0.81 | CYP2D6 (0.53) | ACHECYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL26575270 | 0.79 | CYP2D6 (0.50) | ACHECYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL31669513 | 0.79 | CHRNA1 (0.51) | ACHECYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL17319361 | 0.79 | SLC6A2 (0.53) | ACHECYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL15332985 | 0.78 | ACHE (0.49) | ACHECYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL11172155 | 0.78 | OPRM1 (0.46) | CYP2D6ADRB1ADRA1AOPRM1OPRD1 | |
| SCHEMBL30341013 | 0.77 | SLC6A2 (0.54) | ACHECYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL8983562 | 0.77 | CYP2D6 (0.83) | CYP2D6MC4ROPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417574-A | 2,4 disubstituted benzene ethanone compounds and its optical isomer, pharmaceutically acceptable salt and application | 浙江省医学科学院 | 2017-12-01 | — | — | CN | disclosed |
| EP-0024510-B1 | PHENOXYPROPYL AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1983-10-19 | — | — | EP | disclosed |
| US-4293557-A | AMIDES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| EP-0024510-A1 | Phenoxypropyl amine derivatives, process for their preparation, and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1981-03-11 | — | — | EP | disclosed |