Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933158 | 0.85 | DRD2 (0.45) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL13433740 | 0.79 | GAA (0.47) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL31190634 | 0.76 | ELANE (0.48) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL27920146 | 0.76 | SIGMAR1 (0.51) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL18209820 | 0.76 | SIGMAR1 (0.47) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL18209886 | 0.76 | SIGMAR1 (0.47) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL3922841 | 0.76 | SIGMAR1 (0.47) | ALDH1A1KMT2ALMNASIGMAR1GAA | |
| SCHEMBL18209839 | 0.75 | SIGMAR1 (0.43) | ALDH1A1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL13933094 | 0.75 | GAA (0.47) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL11185258 | 0.74 | SIGMAR1 (0.46) | ALDH1A1MAPTKMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387230-A | Process for preparing a dihydropyridine derivative | JOHN WYETH AND BROTHER LIMITED (GB) | 1983-06-07 | — | — | US | disclosed |