Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383691 | 0.77 | SMN1; SMN2 (0.32) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL16968399 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11335733 | 0.76 | TDP1 (0.50) | TSHRALDH1A1TP53MEN1KMT2A | |
| SCHEMBL10050541 | 0.76 | TSHR (0.76) | TSHRCYP2C9ALDH1A1HPGDTP53 | |
| SCHEMBL8510541 | 0.75 | HPGD (0.49) | TSHRALDH1A1HPGDTP53MAPT | |
| SCHEMBL10050546 | 0.73 | TSHR (0.70) | TSHRCYP2C9ALDH1A1HPGDTP53 | |
| SCHEMBL20457156 | 0.72 | KMT2A (0.78) | TSHRALDH1A1HPGDTP53MAPT | |
| SCHEMBL20457158 | 0.72 | ALDH1A1 (0.68) | TSHRCYP2C9ALDH1A1HPGDTP53 | |
| SCHEMBL11322753 | 0.71 | TDP1 (0.44) | TSHRALDH1A1TP53MEN1KMT2A | |
| SCHEMBL11322757 | 0.71 | TDP1 (0.44) | TSHRALDH1A1TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4383054-A | Hydrophilic high polymers prepared from aqueous solutions or dispersions of polyoxypropylene polyamine N-N'-polymethylene sulfonates | TEXACO INC. (US) | 1983-05-10 | — | — | US | disclosed |
| US-4272384-A | Composition for preventing a resin system from setting up in a well bore | THE DOW CHEMICAL COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4189002-A | Method for rigless zone abandonment using internally catalyzed resin system | THE DOW CHEMICAL COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4101474-A | Aqueous based epoxy slurry for forming a consolidated gravel pack | THE DOW CHEMICAL COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4081030-A | EPOXY RESIN, CURING AGENT, SOLVENT, COUPLING AGENT, QUATERNARY AMMONIUM HALIDE SURFACTANT, AND A PARTICULATE MATERIAL | THE DOW CHEMICAL COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4074760-A | OIL RECOVERY | THE DOW CHEMICAL COMPANY (US) | 1978-02-21 | — | — | US | disclosed |