Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335733 | 0.88 | TDP1 (0.50) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11322753 | 0.80 | TDP1 (0.44) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11332347 | 0.75 | SMN1; SMN2 (0.49) | TDP1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11335740 | 0.72 | TDP1 (0.51) | TDP1MEN1KMT2ASMN1; SMN2ADRA1A | |
| SCHEMBL11336672 | 0.72 | HTT (0.40) | MEN1KMT2ATSHR | |
| SCHEMBL11181589 | 0.71 | TSHR (0.49) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| Ether SCHEMBL8459075 | 0.71 | TDP1 (0.79) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11660769 | 0.70 | TDP1 (0.57) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL28825363 | 0.70 | TDP1 (0.47) | TDP1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL11047634 | 0.70 | TDP1 (0.56) | TDP1KMT2ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259236-A | COLORFAST RED SHADES ON POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |