Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014821 | 0.73 | TDP1 (0.33) | TSHRCYP3A4KDM4EALDH1A1MAPK1 | |
| SCHEMBL29290531 | 0.73 | ADRB1 (0.50) | ADRB1ADRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6374033 | 0.72 | ADRB1 (0.50) | ADRB1ADRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13014490 | 0.70 | ACHE (0.38) | ADRA1ACYP2D6MAPK1 | |
| SCHEMBL4311640 | 0.70 | TDP1 (0.44) | ADRB1ADRB2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL11129369 | 0.70 | CYP3A4 (0.51) | ADRB1ADRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6323504 | 0.69 | ADRB1 (0.56) | ADRB1ADRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12121859 | 0.69 | SLC6A2 (0.46) | ADRB2SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL2783428 | 0.69 | AOC3 (0.39) | SLC6A2SLC6A3LMNAADRA1ATSHR | |
| SCHEMBL3983553 | 0.69 | ADRB1 (0.56) | ADRB1ADRB2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407819-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1983-10-04 | — | — | US | claimed |