SCHEMBL111826

SCHEMBL111826

O=C(O)c1cccc2cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.70
ALDH1A1 P00352 6/20 0.70
LMNA P02545 3/20 0.70
ALOX12 P18054 2/20 0.70
KDM4E B2RXH2 6/20 0.59
TDP1 Q9NUW8 2/20 0.59
TSHR P16473 4/20 0.57
MAPT P10636 3/20 0.57
CYP3A4 P08684 2/20 0.57
ALOX15 P16050 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
BLM P54132 1/20 0.57
AGER Q15109 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
NAPRT Q6XQN6 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.54
CASP3 P42574 1/20 0.54
RAB9A P51151 1/20 0.54
SENP8 Q96LD8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29749881 1.00 PARP1 (0.70) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL31120780 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL28875211 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL27593762 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
Hydrochloric Acid SCHEMBL7320778 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL30006639 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
Hydrochloric Acid SCHEMBL9691259 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
Water SCHEMBL28396801 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL16859274 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL27738328 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1805 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136947-A 4-Androstenedione derivative and preparation method and application thereof 华东师范大学 2025-06-13 CN claimed
CN-118767643-B Formaldehyde-removing color-changing gel and preparation method thereof 青岛众祥环保科技有限公司 2025-03-07 CN claimed
CN-118767643-A Formaldehyde-removing color-changing gel and preparation method thereof 青岛众祥环保科技有限公司 2024-10-15 CN claimed
CN-116376642-B Environment-friendly nano insulator cleaning agent and preparation method thereof 北京中铁科新材料技术有限公司 2024-03-22 CN claimed
CN-117586477-A Modified epoxy resin, preparation method and application thereof, and modified aqueous epoxy emulsion 江苏富琪森新材料有限公司 2024-02-23 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-117467101-A Preparation method of blocked isocyanate cross-linking agent for low-temperature deblocking 杭州美高华颐化工有限公司 2024-01-30 CN claimed
CN-117164868-A Molecularly imprinted polymer, preparation method thereof and application thereof in detection of synthetic cannabinoid 东南大学 2023-12-05 CN claimed
WO-2023163878-A1 ETCHING COMPOSITIONS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2023-08-31 WO claimed
US-20230274946-A1 ETCHING COMPOSITIONS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2023-08-31 US claimed
EP-0144776-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-10-11 EP claimed
US-4832731-A Quinoline-8-carboxylic acid azolides and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1989-05-23 US claimed
US-4808212-A Oxime esters of substituted quinoline-8-carboxylic acids and use thereof as herbicides BASF AKTIENGESELLSCHAFT (DE) 1989-02-28 US claimed
EP-0277631-A1 Process for the preparation of substituted 3-alkyl-quinoline-8-carboxylic acid BASF Aktiengesellschaft (DE) 1988-08-10 EP claimed
EP-0270889-A1 Use of 7-chloroquinoline-8-carboxylic acids for influencing the development of crops BASF Aktiengesellschaft (DE) 1988-06-15 EP claimed
US-4427762-A DEVELOPMENT WITH ALKALINE DEVELOPER MIXTURE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-01-24 US claimed
EP-0082015-A1 Method of forming an image with a photographic cuprous halide material KONICA CORPORATION (JP) 1983-06-22 EP claimed
US-4321172-A Organic polymers with acylurea repeating units having tertiary amino groups pendant therefrom and cathodic electrocoating of said polymers DESOTO, INC. (US) 1982-03-23 US claimed
US-3959473-A DIURETIC U.S. PHILIPS CORPORATION (US) 1976-05-25 US claimed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US claimed