SCHEMBL29749881

SCHEMBL29749881

O=C(O)c1cccc2cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.70
ALDH1A1 P00352 6/20 0.70
LMNA P02545 3/20 0.70
ALOX12 P18054 2/20 0.70
KDM4E B2RXH2 6/20 0.59
TDP1 Q9NUW8 2/20 0.59
TSHR P16473 4/20 0.57
MAPT P10636 3/20 0.57
CYP3A4 P08684 2/20 0.57
ALOX15 P16050 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
BLM P54132 1/20 0.57
AGER Q15109 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
NAPRT Q6XQN6 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.54
CASP3 P42574 1/20 0.54
RAB9A P51151 1/20 0.54
SENP8 Q96LD8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111826 1.00 PARP1 (0.70) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL31120780 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL28875211 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL27593762 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
Hydrochloric Acid SCHEMBL7320778 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL30006639 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
Hydrochloric Acid SCHEMBL9691259 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
Water SCHEMBL28396801 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL16859274 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E
SCHEMBL27738328 0.98 PARP1 (0.68) PARP1ALDH1A1LMNAALOX12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025238576-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION Nuovo Pignone Tecnologie – S.r.l. (IT) 2025-11-20 WO disclosed
WO-2025235613-A1 WATER SPLITTING SYSTEM AND METHOD PURDUE RESEARCH FOUNDATION (US) 2025-11-13 WO disclosed
US-20230330099-A1 SUBSTITUTED INDOLE MCL-1 INHIBITORS VANDERBILT UNIVERSITY 2023-10-19 US disclosed
WO-2023163878-A1 ETCHING COMPOSITIONS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2023-08-31 WO disclosed
EP-4055013-A1 WDR5 INHIBITORS AND MODULATORS Vanderbilt University (US) 2022-09-14 EP disclosed
EP-4021406-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2022-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330099-A1 SUBSTITUTED INDOLE MCL-1 INHIBITORS MCL1, BCL2L1, BCL9 PARP1 230/4885ALDH1A1 2556/4885LMNA 3021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.