Nitrilotriacetic Acid

Nitrilotriacetic Acid

SCHEMBL1118282

CCCCCCCCCCCCCCNCCCCCCCCCCCCCC.O=C(O)CN(CC(=O)O)CC(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.52
ALDH1A1 P00352 3/20 0.52
S1PR2 O95136 5/20 0.48
S1PR4 O95977 5/20 0.48
S1PR1 P21453 5/20 0.48
S1PR3 Q99500 5/20 0.48
S1PR5 Q9H228 1/20 0.48
EPHX1 P07099 4/20 0.47
GPR84 Q9NQS5 6/20 0.45
PPARG P37231 6/20 0.45
PPARD Q03181 6/20 0.45
PPARA Q07869 6/20 0.45
HDAC11 Q96DB2 5/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45
PTPN1 P18031 2/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
SLC22A8 Q8TCC7 1/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrilotriacetic Acid SCHEMBL3154724 1.00 TSHR (0.52) TSHRALDH1A1S1PR2S1PR4S1PR1
Edetic Acid SCHEMBL10949676 0.92 TDP1 (0.52) TSHRALDH1A1S1PR2S1PR4S1PR1
Nitrilotriacetic Acid SCHEMBL10949360 0.92 TSHR (0.44) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL133298 0.91 TSHR (0.46) TSHRALDH1A1S1PR2S1PR4S1PR1
Hydrochloric Acid SCHEMBL4538285 0.89 TSHR (0.45) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL31347643 0.88 PAOX (0.49) TSHRALDH1A1S1PR2S1PR4S1PR1
Nitrilotriacetic Acid SCHEMBL28857186 0.87 GPR84 (0.56) TSHRALDH1A1GPR84PPARGPPARD
SCHEMBL355144 0.85 PAOX (0.43) TSHRALDH1A1S1PR2S1PR4S1PR1
Edetic Acid SCHEMBL10950081 0.84 TDP1 (0.56) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL11585916 0.84 TSHR (0.39) TSHRALDH1A1S1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207614-B Chimeric proteins 利普泰克有限公司 2022-01-11 CN claimed
EP-2906717-B1 METHOD OF PAINTING MICROVESICLES VIN DE BONA TRADING COMPANY PTE LTE (SG) 2018-12-05 EP claimed
US-20180185472-A1 METHOD OF PAINTING MICROVESICLES VIN DE BONA TRADING COMPANY PTE LTD (SG) 2018-07-05 US claimed
US-20180185464-A1 CHIMERIC PROTEINS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2018-07-05 US claimed
US-9919046-B2 Post release modification of viral envelopes VIN DE BONA TRADING CO. PTE LTD (SG) 2018-03-20 US claimed
EP-3204427-A1 CHIMERIC PROTEINS Lipotek Pty Ltd (AU) 2017-08-16 EP claimed
US-20160206730-A1 POST RELEASE MODIFICATION OF VIRAL ENVELOPES VIN DE BONA TRADING CO. PTE LTD (SG) 2016-07-21 US claimed
WO-2016054696-A1 CHIMERIC PROTEINS LIPOTEK PTY LTD (AU) 2016-04-14 WO claimed
US-20150233800-A1 METHOD OF PAINTING MICROVESICLES VIN-DE-BONA TRADING COMPANY PTE LTD (SG) 2015-08-20 US claimed
EP-2906717-A2 METHOD OF PAINTING MICROVESICLES Vin-de-Bona Trading Company Pte Lte (SG) 2015-08-19 EP claimed
EP-2281033-B1 POST RELEASE MODIFICATION OF VIRAL ENVELOPES VIN DE BONA TRADING CO PTE (SG) 2014-10-15 EP claimed
US-20110070164-A1 POST RELEASE MODIFICATION OF VIRAL ENVELOPES VIN DE BONA TRADING CO. PTE LTD (SG) 2011-03-24 US claimed
EP-1660040-B1 IN VIVO TARGETING OF DENDRITIC CELLS LIPOTEK PTY LTD (AU) 2010-02-24 EP claimed
US-20070026057-A1 In vivo targeting of dendritic cells LIPOTEK PTY LTD. (AU) 2007-02-01 US claimed
EP-1660040-A1 IN VIVO TARGETING OF DENDRITIC CELLS Lipotek Pty Ltd. (AU) 2006-05-31 EP claimed
WO-2005018610-A1 IN VIVO TARGETING OF DENDRITIC CELLS LIPOTEK PTY LTD (AU) 2005-03-03 WO claimed
US-20040146948-A1 Compositions and methods for targeting antigen-presenting cells with antibody single-chain variable region fragments CENTENARY INSTITUTE OF CANCER MEDICINE AND CELL BIOLOGY (AU) 2004-07-29 US claimed
US-20240148855-A1 CANCER VACCINE AND METHOD OF USE THEREOF NE1 INC. 2024-05-09 US disclosed
EP-1180042-A1 MODEL MEMBRANE SYSTEMS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2002-02-20 EP disclosed
WO-2000064471-A1 MODEL MEMBRANE SYSTEMS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2000-11-02 WO disclosed