Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891709 | 0.85 | SLC2A1 (0.53) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL11315777 | 0.83 | SLC2A1 (0.51) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL11176635 | 0.82 | ADRB3 (0.54) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL10838597 | 0.82 | CASR (0.55) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL11185331 | 0.78 | SLC2A1 (0.71) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL11349555 | 0.76 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL10963417 | 0.76 | CYP2D6 (0.42) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4656006 | 0.75 | ADRB3 (0.60) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL10893060 | 0.75 | ADRB3 (0.58) | ADRB3ADRB1ADRB2SLC2A1 | |
| SCHEMBL9640850 | 0.75 | ADRB2 (0.56) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028105-B1 | SECONDARY AMINES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | disclosed |
| US-4329358-A | 3-Chlorophenyl anti-obesity agents | BEECHAM GROUP LIMITED (GB) | 1982-05-11 | — | — | US | disclosed |
| EP-0028105-A1 | Secondary amines, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-06 | — | — | EP | disclosed |