Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315777 | 0.88 | SLC2A1 (0.51) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL10893060 | 0.88 | ADRB3 (0.58) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL10838597 | 0.87 | CASR (0.55) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL11176635 | 0.85 | ADRB3 (0.54) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL10892969 | 0.85 | ADRB2 (0.50) | ADRB3ADRB1ADRB2 | |
| SCHEMBL11184232 | 0.85 | ADRB3 (0.52) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL10897293 | 0.84 | ADRB2 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL10889312 | 0.83 | ADRB3 (0.67) | ADRB3ADRB1 | |
| SCHEMBL4656006 | 0.81 | ADRB3 (0.60) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL10891737 | 0.81 | ADRB3 (0.58) | SLC2A1ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588749-A | ANTIOBESITY AND HYPOGLYCEMIC AGENTS | BEECHAM GROUP P.L.C. (GB) | 1986-05-13 | — | — | US | disclosed |
| EP-0040000-B1 | ARYLETHANOLAMINE DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1983-10-12 | — | — | EP | disclosed |
| EP-0040000-A1 | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-11-18 | — | — | EP | disclosed |