SCHEMBL159798

SCHEMBL159798

c1ccc2[nH]c(SSc3nc4ccccc4[nH]3)nc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TXN P10599 2/20 0.72
BCHE P06276 1/20 0.68
POLB P06746 3/20 0.63
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
RAB9A P51151 5/20 0.59
NPC1 O15118 4/20 0.59
EPHX2 P34913 1/20 0.59
SMN1; SMN2 Q16637 4/20 0.58
ALDH1A1 P00352 4/20 0.58
KDM4E B2RXH2 2/20 0.58
TP53 P04637 2/20 0.58
HSD17B10 Q99714 2/20 0.58
ABCB11 O95342 1/20 0.58
PKM P14618 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
AR P10275 1/20 0.58
MAPT P10636 1/20 0.56
STAT3 P40763 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31019381 0.98 TXN (0.70) TXNBCHEPOLBKMT2AMEN1
SCHEMBL3688773 0.98 TXN (0.70) TXNBCHEPOLBKMT2AMEN1
SCHEMBL3792726 0.86 BCHE (0.68) TXNBCHEPOLBKMT2AMEN1
SCHEMBL11823551 0.86 TXN (0.75) TXNBCHEPOLBKMT2AMEN1
SCHEMBL14406847 0.85 TXN (1.00) TXNBCHEPOLBKMT2AMEN1
SCHEMBL10352132 0.83 POLB (0.70) TXNBCHEPOLBKMT2AMEN1
SCHEMBL11307167 0.83 TXN (1.00) TXNBCHEPOLBKMT2AMEN1
SCHEMBL9399224 0.83 BCHE (0.63) TXNBCHEPOLBKMT2AMEN1
SCHEMBL8077898 0.83 BCHE (0.63) TXNBCHEPOLBKMT2AMEN1
SCHEMBL374735 0.83 POLB (0.65) TXNBCHEPOLBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467846-A A kind of wear-resisting resistance to migration high resiliency foot pad material 陈桂芳 2019-03-15 CN claimed
US-9119307-B2 Housing for a portable electronic device TICONA LLC (US) 2015-08-25 US claimed
WO-2015122942-A1 MOLDED PART FOR USE IN A PORTABLE ELECTRONIC DEVICE TICONA LLC (US) 2015-08-20 WO claimed
WO-2015122941-A1 TOUGHENED POLYARYLENE SULFIDE COMPOSITION TICONA LLC (US) 2015-08-20 WO claimed
US-20150225547-A1 Molded Part for Use in a Portable Electronic Device TICONA LLC 2015-08-13 US claimed
US-20150225567-A1 Toughened Polyarylene Sulfide Composition TICONA LLC 2015-08-13 US claimed
US-20140170415-A1 Multicomponent Fiber Containing a Polyarylene Sulfide TICONA LLC (US) 2014-06-19 US claimed
US-20130249357-A1 Housing for a Portable Electronic Device TICONA LLC (US) 2013-09-26 US claimed
WO-2013052269-A2 HOUSING FOR A PORTABLE ELECTRONIC DEVICE TICONA LLC (US) 2013-04-11 WO claimed
EP-1460065-B1 PROCESSES FOR PRODUCTION OF CYCLIC DIAMINE COMPOUNDS OR SALTS THEREOF KOWA CO (JP) 2012-12-05 EP claimed
US-6998486-B2 Process for production of cyclic diamine compounds or salts thereof KOWA CO., LTD. (JP) 2006-02-14 US claimed
US-20050032814-A1 Process for production of cyclic diamine compounds or salts thereof KOWA CO., LTD. (JP) 2005-02-10 US claimed
EP-1460065-A1 PROCESSES FOR PRODUCTION OF CYCLIC DIAMINE COMPOUNDS OR SALTS THEREOF Kowa Co., Ltd. (JP) 2004-09-22 EP claimed
US-20030176512-A1 Asymmetric disulfides and methods of using same PROLX PHARMACEUTICALS CORPORATION (CA) 2003-09-18 US claimed
US-4694015-A TREATING DREPANOCYTOSIS, MALARIA, AND BABEBIOSIS SANOFI (FR) 1987-09-15 US claimed
JP-4208223-A None JP disclosed
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide TICONA LLC (US) 2026-02-12 US disclosed
US-4694015-A TREATING DREPANOCYTOSIS, MALARIA, AND BABEBIOSIS SANOFI (FR) 1987-09-15 US disclosed
EP-0225471-A1 Polyphenylene sulfide containing covalently bonded chlorine in a reduced amount and process for producing the same Tosoh Corporation (JP) 1987-06-16 EP disclosed
EP-0040506-A2 Reactive polymer and process for the preparation thereof TEIJIN LIMITED (JP) 1981-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide SLC39A3, SLC39A11, SLC39A14 TXN 1288/4885BCHE 3560/4885POLB 1969/4885
US-20050032814-A1 Process for production of cyclic diamine compounds or salts thereof SRM, DDC, QDPR TXN 2058/4885BCHE 422/4885POLB 252/4885
US-20030176512-A1 Asymmetric disulfides and methods of using same PRDX3, PDIA5, PRDX5 TXN 11/4885BCHE 3581/4885POLB 2559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.