Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178712 | 0.87 | POLB (0.55) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL11192854 | 0.86 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL11189426 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL11198118 | 0.83 | POLB (0.54) | ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL11165531 | 0.83 | MCHR1 (0.55) | MAPTLMNAPOLB | |
| SCHEMBL11200220 | 0.83 | POLB (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL11165965 | 0.83 | MCHR1 (0.55) | MAPTLMNAPOLB | |
| SCHEMBL11194691 | 0.83 | POLB (0.52) | ALDH1A1MAPTLMNAPOLBPAX8 | |
| SCHEMBL10356773 | 0.83 | MCHR1 (0.55) | MAPTLMNAPOLB | |
| SCHEMBL11441498 | 0.82 | MCHR1 (0.56) | SMN1; SMN2MAPTLMNAPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |