Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11176374 | 0.90 | NOS3 (0.41) | NOS3NOS1NOS2HTR2CHTR2B | |
| SCHEMBL11193502 | 0.84 | NOS3 (0.40) | NOS3NOS1NOS2HTR2CHTR2B | |
| Acetic Acid SCHEMBL11190215 | 0.83 | NOS3 (0.40) | NOS3NOS1NOS2HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL11187059 | 0.83 | NOS3 (0.39) | NOS3NOS1NOS2HTR2CHTR2B | |
| Acetic Acid SCHEMBL11189325 | 0.82 | NOS3 (0.39) | NOS3NOS1NOS2HTR2CHTR2B | |
| Acetic Acid SCHEMBL11185261 | 0.82 | NOS3 (0.39) | NOS3NOS1NOS2HTR2CHTR2B | |
| Sulfuric Acid SCHEMBL11183838 | 0.82 | LMNA (0.39) | NOS3NOS1NOS2HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL11191691 | 0.81 | NOS3 (0.38) | NOS3NOS1NOS2HTR2CHTR2B | |
| Acetic Acid SCHEMBL11185263 | 0.81 | NOS3 (0.39) | NOS3NOS1NOS2HTR2CHTR2B | |
| Acetic Acid SCHEMBL11189328 | 0.81 | NOS3 (0.39) | NOS3NOS1NOS2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001663-B1 | NOVEL 2-ARYLAMINO-HEXAHYDROPYRIMIDINES AND -IMIDAZOLIDINES, SALTS AND COMPLEXES THEREOF, METHOD OF PREPARING THE NOVEL COMPOUNDS AND FUNGICIDAL COMPOSITIONS WHICH CONTAIN THE NOVEL COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-05-12 | — | — | EP | claimed |
| US-4396617-A | FUNGICIDES | DUPHAR INTERNATIONAL B.V. (NL) | 1983-08-02 | — | — | US | disclosed |
| US-4374143-A | AS FUNGICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-02-15 | — | — | US | disclosed |
| EP-0001663-B1 | NOVEL 2-ARYLAMINO-HEXAHYDROPYRIMIDINES AND -IMIDAZOLIDINES, SALTS AND COMPLEXES THEREOF, METHOD OF PREPARING THE NOVEL COMPOUNDS AND FUNGICIDAL COMPOSITIONS WHICH CONTAIN THE NOVEL COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-05-12 | — | — | EP | disclosed |
| EP-0001663-A1 | Novel 2-arylamino-hexahydropyrimidines and -imidazolidines, salts and complexes thereof, method of preparing the novel compounds and fungicidal compositions which contain the novel compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1979-05-02 | — | — | EP | disclosed |