SCHEMBL111865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL112690	0.93	GPR6 (0.42)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL111940	0.89	KMT2A (0.51)	ALDH1A1MEN1KMT2APOLBNPC1
	SCHEMBL111736	0.87	MAPT (0.44)	ALDH1A1KMT2APOLBNPC1RAB9A
	SCHEMBL111068	0.86	JAK2 (0.46)	ALDH1A1MEN1KMT2APOLBNPC1
	SCHEMBL112923	0.86	SMN1; SMN2 (0.56)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL159855	0.80	TRPV1 (0.40)	KDM4EJAK2SMN1; SMN2
	SCHEMBL111877	0.79	TYK2 (0.39)	ALDH1A1KMT2APOLBJAK2GAA
	SCHEMBL112630	0.79	NPC1 (0.48)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL111332	0.78	SMN1; SMN2 (0.60)	ALDH1A1MEN1KMT2AKDM4EPOLB
	SCHEMBL110553	0.78	RAB9A (0.42)	ALDH1A1KDM4EPOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.