Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187333 | 1.00 | TSHR (0.55) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL10777249 | 0.85 | CA1 (0.53) | TSHRCA1CA2CA12CA9 | |
| Acetic Acid SCHEMBL10773789 | 0.84 | CES2 (0.52) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL7473286 | 0.83 | MAPT (0.56) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL15441153 | 0.82 | TSHR (0.57) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL8730101 | 0.82 | CES2 (0.65) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL4408604 | 0.82 | CA1 (0.66) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL14487959 | 0.82 | CA1 (0.59) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL6950525 | 0.81 | TSHR (0.55) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL7680553 | 0.80 | TSHR (0.50) | TSHRCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417053-A | Process for the preparation of substituted glyoxylic acid derivatives | STAMICARBON B.V. (NL) | 1983-11-22 | — | — | US | disclosed |