Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.65 |
| ▸ | CES1 | P23141 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoin SCHEMBL342417 | 0.95 | LMNA (0.72) | CES2CES1LMNATSHRROCK2 | |
| SCHEMBL8730105 | 0.95 | LMNA (0.67) | CES2CES1LMNATSHRROCK2 | |
| SCHEMBL10777249 | 0.93 | CA1 (0.53) | CES2CES1LMNATSHRROCK2 | |
| Acetic Acid SCHEMBL10773789 | 0.92 | CES2 (0.52) | CES2CES1LMNATSHRROCK2 | |
| Benzoin SCHEMBL28155451 | 0.84 | LMNA (0.84) | CES2CES1LMNATSHRROCK2 | |
| Benzoin SCHEMBL26159 | 0.84 | LMNA (0.84) | CES2CES1LMNATSHRROCK2 | |
| Benzoin SCHEMBL28231195 | 0.84 | LMNA (0.84) | CES2CES1LMNATSHRROCK2 | |
| Benzoin SCHEMBL4910212 | 0.84 | LMNA (0.84) | CES2CES1LMNATSHRROCK2 | |
| SCHEMBL17585020 | 0.83 | L3MBTL1 (0.67) | TSHRROCK2ALDH1A1RAB9AMAPT | |
| Benzoin SCHEMBL31362056 | 0.83 | LMNA (0.75) | CES2CES1LMNATSHRROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817826-A | INHIBIT FORMATION OF PROSTAGLANDINS, LEUKOTRIENES; ANTIINFLAMMATION AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0675114-A1 | OXAZOLINONE DERIVATIVE HAVING INTRACELLULAR PHOSPHOLIPASE A 2? INHIBITOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |