Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052201 | 0.84 | MAPT (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL30528867 | 0.84 | MAPT (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL1052199 | 0.84 | MAPT (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL20513717 | 0.83 | MAPT (0.65) | KDM4EMAPTMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL20513716 | 0.83 | MAPT (0.65) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL22622531 | 0.82 | KDM4E (0.72) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL13323168 | 0.82 | KDM4E (0.72) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL13906881 | 0.82 | KDM4E (0.72) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL20599963 | 0.77 | HTR2A (0.63) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL2633083 | 0.75 | DAO (0.50) | KDM4EMAPTMEN1KMT2AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4378368-A | Use of 4-(2-di-n-propylaminoethyl)indole or a salt thereof as a presynaptic dopamine autoreceptor stimulant | PURDUE RESEARCH FOUNDATION (US) | 1983-03-29 | — | — | US | disclosed |