Sugi Predict

Sugi Predict / Compounds / SCHEMBL1052201

SCHEMBL1052201

SCHEMBL1052201

N[C@@H](Cc1cccc2[nH]ccc12)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.67
▸ KMT2A Q03164 4/20 0.67
▸ KDM4E B2RXH2 4/20 0.67
▸ LMNA P02545 3/20 0.67
▸ BLM P54132 3/20 0.67
▸ PMP22 Q01453 3/20 0.67
▸ MEN1 O00255 3/20 0.67
▸ TSHR P16473 2/20 0.67
▸ HIF1A Q16665 2/20 0.67
▸ MPO P05164 1/20 0.67
▸ ALDH1A1 P00352 3/20 0.51
▸ CYP3A4 P08684 2/20 0.51
▸ ALOX15 P16050 2/20 0.51
▸ NFKB1 P19838 2/20 0.51
▸ NPSR1 Q6W5P4 2/20 0.51
▸ HSD17B10 Q99714 2/20 0.51
▸ HTR1A P08908 1/20 0.51
▸ ADORA3 P0DMS8 1/20 0.51
▸ HTR2A P28223 1/20 0.51
▸ HTR2C P28335 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30528867 1.00 MAPT (0.67) MAPTKMT2AKDM4ELMNABLM
SCHEMBL1052199 1.00 MAPT (0.67) MAPTKMT2AKDM4ELMNABLM
Hydrochloric Acid SCHEMBL20513716 0.98 MAPT (0.65) MAPTKMT2AKDM4ELMNABLM
Hydrochloric Acid SCHEMBL20513717 0.98 MAPT (0.65) MAPTKMT2AKDM4ELMNABLM
SCHEMBL5326606 0.85 KDM4E (0.52) MAPTKMT2AKDM4ELMNABLM
SCHEMBL11189552 0.84 KDM4E (0.48) MAPTKMT2AKDM4ELMNABLM
Dl-Tryptophan SCHEMBL27962058 0.82 KDM4E (0.97) MAPTKMT2AKDM4ELMNABLM
Tryptophan SCHEMBL27962055 0.82 KDM4E (0.97) MAPTKMT2AKDM4ELMNABLM
SCHEMBL14282895 0.80 ITGB2 (0.46) MAPTKMT2AKDM4ELMNABLM
Tryptophan SCHEMBL23141133 0.80 KMT2A (1.00) MAPTKMT2AKDM4ELMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303647-A1 CYCLIC CHEMERIN-9 DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2023-09-28 — — US claimed
CN-116390742-A Cyclic chemokine-9 derivatives 拜耳公司 2023-07-04 — — CN claimed
EP-4196143-A1 CYCLIC CHEMERIN-9 DERIVATIVES Bayer Aktiengesellschaft (DE) 2023-06-21 — — EP claimed
WO-2022034057-A1 CYCLIC CHEMERIN-9 DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2022-02-17 — — WO claimed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 — — EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 — — US disclosed
CN-114585637-B MASP-inhibitory compounds and uses thereof 拜耳公司 2025-04-15 — — CN disclosed
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 — — US disclosed
US-20230303647-A1 CYCLIC CHEMERIN-9 DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2023-09-28 — — US disclosed
CN-116390742-A Cyclic chemokine-9 derivatives 拜耳公司 2023-07-04 — — CN disclosed
EP-4196143-A1 CYCLIC CHEMERIN-9 DERIVATIVES Bayer Aktiengesellschaft (DE) 2023-06-21 — — EP disclosed
US-11667675-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2023-06-06 — — US disclosed
US-20040220108-A1 Neo-tryptophan MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, A MINNESOTA CORPORATION 2004-11-04 — — US disclosed
US-6765099-B2 NOVEL AMINO ACID, NEO-TRYPTOPHAN, AS WELL AS POLYPEPTIDES CONTAINING THIS NOVEL AMINO ACID SUCH AS NEUROTENSIN ANALOGS. IN ADDITION, THE INVENTION PROVIDES NEO- TRYPTOPHAN DERIVATIVES, SEROTONIN-LIKE NEO-TRYPTOPHAN DERIVATIVES AND MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2004-07-20 — — US disclosed
US-20030166505-A1 Neo-tryptophan MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, A MINNESOTA CORPORATION 2003-09-04 — — US disclosed
US-20010027174-A1 Neo-tryptophan MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH MINNESOTA CORPORATION 2001-10-04 — — US disclosed
EP-1067950-A4 NEO-TRYPTOPHAN MAYO FOUNDATION FOR MEDICAL (US) 2001-09-05 — — EP disclosed
US-6214790-B1 POLYPEPTIDES OF NEOTRYPTOPHAN AND SYNTHESIS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2001-04-10 — — US disclosed
EP-1067950-A1 NEO-TRYPTOPHAN MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2001-01-17 — — EP disclosed
WO-1999052539-A1 NEO-TRYPTOPHAN MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1999-10-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 MAPT 4377/4885KMT2A 4690/4885KDM4E 4724/4885
US-20040220108-A1 Neo-tryptophan NTSR1, NTSR2, TPH1 MAPT 2063/4885KMT2A 3065/4885KDM4E 4347/4885
US-20030166505-A1 Neo-tryptophan NTSR1, NTSR2, TPH1 MAPT 2063/4885KMT2A 3065/4885KDM4E 4347/4885
US-20010027174-A1 Neo-tryptophan NTSR1, NTSR2, TPH1 MAPT 2063/4885KMT2A 3065/4885KDM4E 4347/4885
US-20230303647-A1 CYCLIC CHEMERIN-9 DERIVATIVES CMKLR1, CMKLR2, CCL2 MAPT 4465/4885KMT2A 4544/4885KDM4E 4718/4885
US-11667675-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 MAPT 4377/4885KMT2A 4690/4885KDM4E 4724/4885
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 MAPT 4377/4885KMT2A 4690/4885KDM4E 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.