SCHEMBL1052199

SCHEMBL1052199

NC(Cc1cccc2[nH]ccc12)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.67
KMT2A Q03164 4/20 0.67
KDM4E B2RXH2 4/20 0.67
LMNA P02545 3/20 0.67
BLM P54132 3/20 0.67
PMP22 Q01453 3/20 0.67
MEN1 O00255 3/20 0.67
TSHR P16473 2/20 0.67
HIF1A Q16665 2/20 0.67
MPO P05164 1/20 0.67
ALDH1A1 P00352 3/20 0.51
CYP3A4 P08684 2/20 0.51
ALOX15 P16050 2/20 0.51
NFKB1 P19838 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
HSD17B10 Q99714 2/20 0.51
HTR1A P08908 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
HTR2A P28223 1/20 0.51
HTR2C P28335 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1052201 1.00 MAPT (0.67) MAPTKMT2AKDM4ELMNABLM
SCHEMBL30528867 1.00 MAPT (0.67) MAPTKMT2AKDM4ELMNABLM
Hydrochloric Acid SCHEMBL20513716 0.98 MAPT (0.65) MAPTKMT2AKDM4ELMNABLM
Hydrochloric Acid SCHEMBL20513717 0.98 MAPT (0.65) MAPTKMT2AKDM4ELMNABLM
SCHEMBL5326606 0.85 KDM4E (0.52) MAPTKMT2AKDM4ELMNABLM
SCHEMBL11189552 0.84 KDM4E (0.48) MAPTKMT2AKDM4ELMNABLM
Dl-Tryptophan SCHEMBL27962058 0.82 KDM4E (0.97) MAPTKMT2AKDM4ELMNABLM
Tryptophan SCHEMBL27962055 0.82 KDM4E (0.97) MAPTKMT2AKDM4ELMNABLM
SCHEMBL14282895 0.80 ITGB2 (0.46) MAPTKMT2AKDM4ELMNABLM
Tryptophan SCHEMBL23141133 0.80 KMT2A (1.00) MAPTKMT2AKDM4ELMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303647-A1 CYCLIC CHEMERIN-9 DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2023-09-28 US claimed
CN-116390742-A Cyclic chemokine-9 derivatives 拜耳公司 2023-07-04 CN claimed
EP-4196143-A1 CYCLIC CHEMERIN-9 DERIVATIVES Bayer Aktiengesellschaft (DE) 2023-06-21 EP claimed
WO-2022034057-A1 CYCLIC CHEMERIN-9 DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2022-02-17 WO claimed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-20240279731-A1 MULTI COLOR WHOLE-GENOME MAPPING AND SEQUENCING IN NANOCHANNEL FOR GENETIC ANALYSIS DREXEL UNIVERSITY 2024-08-22 US disclosed
EP-4355870-A1 MULTICOLOR WHOLE-GENOME MAPPING AND SEQUENCING IN NANOCHANNEL FOR GENETIC ANALYSIS Drexel University (US) 2024-04-24 EP disclosed
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 US disclosed
CN-117836429-A Multicolor whole genome mapping and sequencing in nanochannels for genetic analysis 德雷克塞尔大学 2024-04-05 CN disclosed
US-20240100184-A1 METHODS OF PRECISE GENOME EDITING BY IN SITU CUT AND PASTE (ICAP) UNIV ROWAN (US) 2024-03-28 US disclosed
US-20240035024-A1 LINKED-READ SEQUENCING LIBRARY PREPARATION UNIV DREXEL (US) 2024-02-01 US disclosed
EP-2454272-A1 NEUROTENSIN ANALOGUES FOR RADIOISOTOPE TARGETING TO NEUROTENSIN RECEPTOR-POSITIVE TUMORS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2012-05-23 EP disclosed
WO-2011006985-A1 NEUROTENSIN ANALOGUES FOR RADIOISOTOPE TARGETING TO NEUROTENSIN RECEPTOR-POSITIVE TUMORS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2011-01-20 WO disclosed
WO-2010085661-A1 MODIFIED PEPTIDES AND THEIR USE MUSC FOUNDATION FOR REASEARCH DEVELOPMENT (US) 2010-07-29 WO disclosed
US-20090105129-A1 Combination therapy XENOME LTD (AU) 2009-04-23 US disclosed
US-20090105129-A1 Combination therapy XENOME LTD (AU) 2009-04-23 US disclosed
US-20090062212-A1 Peptide analogs that are potent and selective for human neurotensin preceptor subtype 2 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2009-03-05 US disclosed
US-20070258899-A1 Diagnostic and therapeutic agents KARYON-CTT LTD (FI) 2007-11-08 US disclosed
WO-2007113385-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 MAPT 4377/4885KMT2A 4690/4885KDM4E 4724/4885
US-20230303647-A1 CYCLIC CHEMERIN-9 DERIVATIVES CMKLR1, CMKLR2, CCL2 MAPT 4465/4885KMT2A 4544/4885KDM4E 4718/4885
US-20090105129-A1 Combination therapy OPRL1, SLC6A2, OPRK1 MAPT 770/4885KMT2A 3222/4885KDM4E 4377/4885
US-20070258899-A1 Diagnostic and therapeutic agents YBX1, MLX, TPX2 MAPT 3794/4885KMT2A 3586/4885KDM4E 2053/4885
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 MAPT 4377/4885KMT2A 4690/4885KDM4E 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.