Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11188087 | 0.89 | MAPT (0.42) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11184565 | 0.85 | L3MBTL1 (0.47) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11197797 | 0.85 | GGT1 (0.48) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL10989509 | 0.83 | GGT1 (0.47) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11186159 | 0.82 | NOX1 (0.40) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11193793 | 0.82 | L3MBTL1 (0.43) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11199300 | 0.82 | GAA (0.46) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11187365 | 0.77 | GAA (0.41) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11188796 | 0.77 | NOX1 (0.46) | L3MBTL1GGT1MAPTGAABCHE | |
| SCHEMBL11193820 | 0.77 | GAA (0.41) | L3MBTL1GGT1MAPTGAABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356302-A | ANOREXIGENIC AGENTS | G. D. SEARLE & CO. (US) | 1982-10-26 | — | — | US | claimed |
| US-4399279-A | ANOREXIGENIC AGENTS | G.D. SEARLE & CO. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4356302-A | ANOREXIGENIC AGENTS | G. D. SEARLE & CO. (US) | 1982-10-26 | — | — | US | disclosed |