Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189757 | 0.78 | — | — | |
| Potassium Ion SCHEMBL11524520 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| Potassium Ion SCHEMBL11775661 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11201161 | 0.72 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL11212835 | 0.72 | — | — | |
| SCHEMBL11232573 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11667782 | 0.67 | ALDH1A1 (0.35) | ALDH1A1TRPA1CYP3A4HPGDALOX15 | |
| SCHEMBL11010528 | 0.66 | TRPA1 (0.36) | ALDH1A1TRPA1CYP3A4HPGDALOX15 | |
| SCHEMBL2143211 | 0.64 | — | — | |
| SCHEMBL4239372 | 0.63 | TRPA1 (0.47) | ALDH1A1TRPA1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4413129-A | FROM 4-METHYL-5-HYDROXYMETHYLIMIDAZOLE AND 2-AMINOETHANETHIOLSULFURIC ACID | SOGO PHARMACEUTICAL COMPANY, LTD. (JP) | 1983-11-01 | — | — | US | disclosed |
| US-RE31244-E | Antihypertensive pyridylguanidine compounds | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1983-05-17 | — | — | US | disclosed |
| US-4179523-A | BACTERICIDES, FUNGICIDES | STAUFFER CHEMICAL COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4124637-A | BACTERICIDES, FUNGICIDES, ALGICIDES | STAUFFER CHEMICAL COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-3959328-A | BACTERICIDE, FUNGICIDE, NEMATOCIDE | BUCKMAN LABORATORIES, INC. (US) | 1976-05-25 | — | — | US | disclosed |