⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667694 | 0.73 | — | — | |
| SCHEMBL3480964 | 0.71 | — | — | |
| SCHEMBL6470841 | 0.69 | — | — | |
| SCHEMBL18467157 | 0.69 | — | — | |
| SCHEMBL4729594 | 0.67 | APP (0.40) | — | |
| Ethylene SCHEMBL28841550 | 0.67 | — | — | |
| SCHEMBL15163723 | 0.67 | CA2 (0.33) | — | |
| SCHEMBL20291899 | 0.66 | DNM1 (0.40) | — | |
| SCHEMBL19285917 | 0.65 | — | — | |
| SCHEMBL28820079 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277635-B1 | Novel polyamine derivatives | MERRELL DOW PHARMA (US) | 1994-01-05 | — | — | EP | claimed |
| EP-0277635-A2 | Novel polyamine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-10 | — | — | EP | claimed |
| CN-110402264-A | AQUEOUS POLYURETHANE DISPERSIONS | LAMBERTI SPA | 2019-11-01 | — | — | CN | disclosed |
| EP-3039015-A1 | SUBSTITUTED PYRIMIDINE BMI-1 INHIBITORS | PTC Therapeutics, Inc. (US) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015030847-A1 | SUBSTITUTED PYRIMIDINE BMI-1 INHIBITORS | PTC THERAPEUTICS, INC. (US) | 2015-03-05 | — | — | WO | disclosed |
| CN-102112510-B | Anionic polyurethane aqueous dispersions | LAMBERTI SPA | 2014-04-16 | — | — | CN | disclosed |
| CN-102112510-A | Anionic polyurethane aqueous dispersions | LAMBERTI SPA | 2011-06-29 | — | — | CN | disclosed |
| EP-2280688-A1 | AQUEOUS PHARMACEUTICAL FORMULATION | Acino Pharma AG (CH) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009124586-A1 | AQUEOUS PHARMACEUTICAL FORMULATION | ARPIDA AG (CH) | 2009-10-15 | — | — | WO | disclosed |
| CN-1263093-A | Amlo dipine mesylate and its preparation and application | KUNMING SAINUO PHARMACEUTICAL (CN) | 2000-08-16 | — | — | CN | disclosed |
| CN-1067429-A | The 4-substituted alkyl carbapenem antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1992-12-30 | — | — | CN | disclosed |