Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392382 | 1.00 | RAPGEF4 (0.47) | RAPGEF4MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11185036 | 1.00 | RAPGEF4 (0.47) | RAPGEF4MEN1KMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL29908518 | 0.98 | RAPGEF4 (0.46) | RAPGEF4MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11477456 | 0.86 | RAPGEF4 (0.47) | RAPGEF4MEN1KMT2AALDH1A1HTT | |
| SCHEMBL11176800 | 0.81 | MAPK1 (0.51) | RAPGEF4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11176798 | 0.81 | MAPK1 (0.51) | RAPGEF4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29386255 | 0.81 | MAPK1 (0.51) | RAPGEF4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3678612 | 0.79 | CYP3A4 (0.51) | RAPGEF4MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL3678614 | 0.79 | CYP3A4 (0.51) | RAPGEF4MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL2093389 | 0.75 | MEN1 (0.50) | RAPGEF4MEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369189-A | INSECTICIDES, MITICIDES NEMATOCIDES | UNION CARBIDE CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |
| US-4331680-A | SUBSTITUTED BENZOPHENONE HYDRAZONE, INSECTICIDES | THE BOOTS COMPANY (GB) | 1982-05-25 | — | — | US | disclosed |
| US-4076837-A | INSECTICIDES, MITICIDES | CIBA-GEIGY CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |