Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678612 | 1.00 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1KDM4EHTT | |
| SCHEMBL4581102 | 0.81 | CYP3A4 (0.58) | CYP3A4ADRA2AALDH1A1KDM4EHTT | |
| SCHEMBL11185036 | 0.79 | RAPGEF4 (0.47) | ALDH1A1HTTRAPGEF4HPGDMEN1 | |
| SCHEMBL6067530 | 0.79 | CYP3A4 (0.56) | CYP3A4ADRA2AALDH1A1KDM4EHTT | |
| SCHEMBL11454683 | 0.79 | CYP3A4 (0.56) | CYP3A4ADRA2AALDH1A1KDM4EHTT | |
| SCHEMBL11190079 | 0.79 | RAPGEF4 (0.47) | ALDH1A1HTTRAPGEF4HPGDMEN1 | |
| SCHEMBL29392382 | 0.79 | RAPGEF4 (0.47) | ALDH1A1HTTRAPGEF4HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL11533363 | 0.78 | CYP3A4 (0.55) | CYP3A4ADRA2AALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL29908518 | 0.78 | RAPGEF4 (0.46) | ALDH1A1HTTRAPGEF4HPGDMEN1 | |
| SCHEMBL8746896 | 0.75 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173728-B2 | Multi-cavity container having offset indentures for dispensing fluids | MERIAL INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-8921408-B2 | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof | MERIAL LIMITED (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140228785-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2014-08-14 | — | — | US | disclosed |
| US-20130256170-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2013-10-03 | — | — | US | disclosed |
| US-8450357-B2 | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof | MERIAL LIMITED (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100125097-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL, INC. | 2010-05-20 | — | — | US | disclosed |
| EP-0640591-B1 | Azomethine derivatives as UV light absorbers | ORIENT CHEMICAL IND (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5523027-A | AZOMETHINE COMPOUNDS; LIGHT RESISTANCE | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0640591-A1 | Azomethine derivatives as UV light absorbers | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130256170-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | TYR, CAT, NAT1 | CYP3A4 37/4885ADRA2A 3113/4885ALDH1A1 766/4885 |
| US-20100125097-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | TYR, CAT, NAT1 | CYP3A4 37/4885ADRA2A 3113/4885ALDH1A1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.