Stepronin

Stepronin

SCHEMBL19338

CC(SC(=O)c1cccs1)C(=O)NCC(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 2/20 0.56
▸ TSHR P16473 3/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ RAB9A P51151 3/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ HPGD P15428 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ ACE P12821 1/20 0.43
▸ MAPT P10636 2/20 0.40
▸ ADAM17 P78536 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ DAO P14920 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stepronin SCHEMBL19339 1.00 ELANE (0.56) ELANETSHRKMT2AMEN1RAB9A
Stepronin SCHEMBL1651441 0.87 ELANE (0.54) ELANETSHRKMT2AMEN1RAB9A
Stepronin SCHEMBL6818585 0.83 ELANE (0.48) ELANETSHRKMT2AMEN1RAB9A
SCHEMBL11176247 0.80 ELANE (0.47) ELANETSHRKMT2AMEN1ALDH1A1
SCHEMBL11189010 0.80 ELANE (0.59) ELANEKMT2AMEN1RAB9AALDH1A1
SCHEMBL11189007 0.80 ELANE (0.59) ELANEKMT2AMEN1RAB9AALDH1A1
SCHEMBL7314482 0.79 ELANE (0.56) ELANEKMT2AMEN1RAB9AALDH1A1
SCHEMBL10505335 0.79 MME (0.48) KMT2AMEN1ALDH1A1HPGDACE
SCHEMBL11188353 0.78 ELANE (0.55) ELANEKMT2ARAB9AALDH1A1HPGD
SCHEMBL11188356 0.78 ELANE (0.55) ELANEKMT2ARAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2249 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 — — US claimed
WO-2025122957-A1 PROTEASE ACTIVATABLE CYTOKINES AND METHODS FOR MAKING AND USING THE SAME AMUNIX PHARMACEUTICALS, INC. (US) 2025-06-12 — — WO claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 — — US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 — — EP claimed
US-20240254098-A1 THIOESTER PRODRUGS FOR THE TREATMENT OF RENAL ANOMALIES ALTIBIO, INC. 2024-08-01 — — US claimed
US-20240165020-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-05-23 — — US claimed
EP-4360653-A2 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2024-05-01 — — EP claimed
US-11872307-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2024-01-16 — — US claimed
EP-3682872-B1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-01-03 — — EP claimed
WO-2023205619-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-10-26 — — WO claimed
WO-2001012584-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2001-02-22 — — WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 — — WO claimed
WO-2000050050-A1 MULTIPARTICULATE FORMULATION ISIS PHARMACEUTICALS, INC. (US) 2000-08-31 — — WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed
WO-1998022114-A1 A METHOD FOR PROMOTING TISSUE REPAIR DUMEX-ALPHARMA A/S (DK) 1998-05-28 — — WO claimed
US-4845114-A N-(trans-p-hydroxy-cyclohexyl)-(2-amino-3,5-dibromo)benzylamine salts possessing mucolytic activity ERREGIERRE INDUSTRIA CHIMICA SPA (IT) 1989-07-04 — — US claimed
EP-0274106-A2 N-(trans-p-hydroxy-cyclohexyl)-(2-amino-3,5-dibromo)benzylamine salts possessing mucolytic activity ERREGIERRE INDUSTRIA CHIMICA Spa (IT) 1988-07-13 — — EP claimed
US-4405638-A ANTITUSSIVE AGENTS; ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) 1983-09-20 — — US claimed
US-4242354-A LIVER DISEASES AND POISONING; MUCOLYTIC AND BRONCHIAL-SPASM RELIEVING MEDIOLANUM FARMACEUTICI S.R.L. (IT) 1980-12-30 — — US claimed
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