Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 4/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183034 | 0.92 | AKR1B10 (0.39) | AKR1B10AKR1B1AKR1A1HTR1AHTR2A | |
| SCHEMBL11188710 | 0.92 | AKR1B10 (0.41) | AKR1B10AKR1B1AKR1A1HTR1AHTR6 | |
| Hydrochloric Acid SCHEMBL11195539 | 0.91 | AKR1B10 (0.40) | AKR1B10AKR1B1AKR1A1HTR1AHTR6 | |
| SCHEMBL11186857 | 0.91 | AKR1B10 (0.39) | AKR1B10AKR1B1AKR1A1HTR1AHTR2A | |
| SCHEMBL11180471 | 0.88 | MEN1 (0.40) | AKR1B10AKR1B1AKR1A1HTR1AMAPT | |
| SCHEMBL11187131 | 0.88 | HTR1A (0.40) | AKR1B10AKR1B1AKR1A1HTR1AHTR2A | |
| SCHEMBL11182485 | 0.86 | HRH2 (0.35) | AKR1B10AKR1B1AKR1A1HTR1AHTR2A | |
| SCHEMBL11177134 | 0.85 | TSHR (0.41) | AKR1B10AKR1B1AKR1A1MAPTCYP2D6 | |
| SCHEMBL11183362 | 0.85 | MAPT (0.38) | AKR1B10AKR1B1AKR1A1HTR1AHTR2A | |
| SCHEMBL11180821 | 0.83 | AKR1B10 (0.36) | AKR1B10AKR1B1AKR1A1HTR7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |