Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228193 | 0.84 | KMT2A (0.58) | GAACHEK2HDAC6KMT2AMEN1 | |
| SCHEMBL11191286 | 0.83 | GAA (0.43) | GAACHEK2HDAC6KMT2AMEN1 | |
| SCHEMBL11184150 | 0.80 | KMT2A (0.53) | CHEK2KMT2AMEN1 | |
| SCHEMBL25909564 | 0.79 | KMT2A (0.52) | CHEK2HDAC6KMT2AMEN1 | |
| SCHEMBL31276700 | 0.79 | KMT2A (0.52) | CHEK2HDAC6KMT2AMEN1 | |
| SCHEMBL11180540 | 0.79 | KMT2A (0.52) | CHEK2HDAC6KMT2AMEN1 | |
| SCHEMBL9063736 | 0.78 | CA2 (0.50) | GAAKMT2AMEN1GRIN1GRIN2B | |
| SCHEMBL2812600 | 0.77 | KMT2A (0.56) | GAAKMT2AMEN1 | |
| SCHEMBL31276938 | 0.76 | KMT2A (0.59) | GAAKMT2AMEN1 | |
| SCHEMBL28325439 | 0.76 | GAA (0.60) | GAACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407823-A | ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0007319-A1 | Indan-1-carboxylic acid derivatives,process for their preparation and pharmaceutical preparations containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-02-06 | — | — | EP | disclosed |