Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 3/20 | 0.45 |
| ▸ | XDH | P47989 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11175911 | 0.97 | KDM4E (0.43) | KDM4ESMN1; SMN2MPOXDHPOLB | |
| SCHEMBL11190717 | 0.85 | KDM4E (0.47) | KDM4EMPOXDHGAAALDH1A1 | |
| SCHEMBL11173096 | 0.80 | MPO (0.47) | MPOXDHHTR6ADRA1AHRH1 | |
| Cadaverine Tartrate SCHEMBL11175456 | 0.77 | MPO (0.41) | MPOXDHHTR6ADRA1AHRH1 | |
| SCHEMBL11190174 | 0.74 | FSCN1 (0.36) | POLBMAPTKMT2A | |
| SCHEMBL11171757 | 0.74 | KMT2A (0.42) | KDM4ESMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL11178382 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11168322 | 0.71 | KMT2A (0.52) | KDM4ERAB9AGAAALDH1A1MAPT | |
| SCHEMBL24182160 | 0.71 | GFER (0.49) | KDM4ESMN1; SMN2RAB9APTGER1GFER | |
| Water SCHEMBL11175216 | 0.71 | BRD4 (0.47) | KDM4EMPOXDHALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393210-A | ANALGESIC, ANTIULCER, ANTIDEPRESSANT, ANTIHISTAMINE, ANTICHOLINERGIC | SEIYAKU CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |