Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 14/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193715 | 0.89 | ADRB2 (0.49) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11203650 | 0.87 | ADRB2 (0.51) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11199082 | 0.86 | ADRB2 (0.55) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11190815 | 0.84 | ADRB1 (0.60) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11189856 | 0.84 | ADRB2 (0.66) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11191861 | 0.83 | ADRB2 (0.50) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11193789 | 0.83 | ADRB2 (0.53) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11195924 | 0.82 | ADRB2 (0.48) | ADRB2ADRB3ADRB1 | |
| SCHEMBL10709904 | 0.79 | ADRB2 (0.59) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11197338 | 0.79 | ADRB2 (0.54) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379166-A | Arylmethoxy-, arylmethylthio-, heteroarylmethoxy-, and heteroarylmethylthio-alkylaminoalcohols | SCHERING CORPORATION (US) | 1983-04-05 | — | — | US | disclosed |