Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190856 | 1.00 | CHRNA7 (0.42) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8900770 | 0.87 | MEN1 (0.44) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8967406 | 0.83 | CHRNA7 (0.42) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8541939 | 0.83 | CHRNA7 (0.42) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8546489 | 0.83 | CHRNA7 (0.42) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8541943 | 0.83 | CHRNA7 (0.42) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL9090924 | 0.79 | CHRNA7 (0.44) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL14011291 | 0.78 | MEN1 (0.51) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL14011287 | 0.78 | MEN1 (0.51) | CHRNA7SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8967316 | 0.75 | SLC6A2 (0.42) | CHRNA7SLC6A2SLC6A4SLC6A3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4419517-A | ANALGESICS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-12-06 | — | — | US | disclosed |