Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3834729 | 0.98 | ATM (0.38) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| Acetic Acid SCHEMBL9774420 | 0.94 | ALDH1A1 (0.37) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL15448304 | 0.91 | SMN1; SMN2 (0.35) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL11373959 | 0.90 | ATM (0.39) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL16838354 | 0.87 | OPRM1 (0.48) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL16837840 | 0.86 | ATM (0.33) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL15448628 | 0.86 | ATM (0.40) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL16837841 | 0.86 | ATM (0.33) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL16837839 | 0.83 | ATM (0.32) | ATMALDH1A1POLBOPRM1SMN1; SMN2 | |
| SCHEMBL9750997 | 0.83 | TSHR (0.37) | ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912512-B | Preparation method of vinyl cyclopropyl ethyl formate compound | 上海合全药业股份有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-113912512-A | Preparation method of vinyl cyclopropyl ethyl formate compound | 上海合全药业股份有限公司 | 2022-01-11 | — | — | CN | claimed |
| CN-105861585-B | A method of hepatitis C NS3 enzyme inhibitor medicine intermediate is split using Sphingomonas | 北京化工大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-103936819-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-105861585-A | Method for splitting hepatitis c NS3 enzyme inhibitor drug intermediate through sphingomonasaquatilis | 北京化工大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-102083821-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-17 | — | — | CN | disclosed |
| CN-103936819-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-23 | — | — | CN | disclosed |
| CN-101903391-B | Process for the preparation of a macrocycle | HOFFMANN LA ROCHE | 2013-04-03 | — | — | CN | disclosed |
| CN-102816170-A | Novel macrocyclic inhibitors of hepatitis C virus replication | INTERMUNE INC | 2012-12-12 | — | — | CN | disclosed |
| CN-102482200-A | Process for preparation of optically active ethyl 1-amino-2-ethenylcyclopropanecarboxylate | SUMITOMO CHEMICAL CO | 2012-05-30 | — | — | CN | disclosed |
| EP-2280958-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-1879910-A2 | TRIPEPTIDES AS HEPATITIS C VIRUS INHIBITORS | Brystol-Myers Squibb Company (US) | 2008-01-23 | — | — | EP | disclosed |
| CN-101024671-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1974596-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-06-06 | — | — | CN | disclosed |
| WO-2007056120-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-18 | — | — | WO | disclosed |
| CN-1299677-C | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-02-14 | — | — | CN | disclosed |
| WO-2006122188-A2 | TRIPEPTIDES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-16 | — | — | WO | disclosed |
| CN-1668297-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2005-09-14 | — | — | CN | disclosed |
| EP-1455809-A2 | INHIBITORS OF HEPATITIS C VIRUS | Bristol-Myers Squibb Company (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053349-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |