Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.70 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11180617 | 0.86 | GAA (0.54) | CDK1CCNB1GLAGAAALOX5 | |
| SCHEMBL11194586 | 0.83 | GAA (0.76) | CDK1CCNB1RXFP1GLAGAA | |
| SCHEMBL6307061 | 0.82 | CDK1 (0.75) | CDK1CCNB1RXFP1GLAGAA | |
| SCHEMBL8325034 | 0.82 | CDK1 (0.63) | CDK1CCNB1RXFP1GLAGAA | |
| SCHEMBL5565082 | 0.78 | KDM4E (0.62) | GLAGAAALOX15KDM4EALDH1A1 | |
| SCHEMBL31437284 | 0.78 | KDM4E (0.62) | GLAGAAALOX15KDM4EALDH1A1 | |
| SCHEMBL11640545 | 0.77 | GPR35 (0.64) | CDK1CCNB1GLAGAAALOX15 | |
| SCHEMBL22042078 | 0.77 | CDK1 (0.58) | CDK1CCNB1RXFP1GLAGAA | |
| SCHEMBL4044123 | 0.77 | CDK1 (0.57) | CDK1CCNB1GLAGAAALOX15 | |
| SCHEMBL4090248 | 0.77 | CDK1 (0.57) | CDK1CCNB1RXFP1GAAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414416-A | Certain diacetyl-amino-phenolic derivatives | FISONS LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| US-4328341-A | Process for preparing certain pyrano[3,2-g]quinoline 2,8-dicarboxylates and 4-oxo-quinoline-2-carboxylates | FISONS LIMITED (GB) | 1982-05-04 | — | — | US | disclosed |