Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723446 | 0.84 | GPR35 (0.68) | GPR35ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11180617 | 0.80 | GAA (0.54) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL18758665 | 0.78 | CDK1 (0.44) | GPR35ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11641819 | 0.78 | GPR35 (1.00) | GPR35ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11190882 | 0.77 | CDK1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11194586 | 0.76 | GAA (0.76) | ALDH1A1KDM4EHPGDPOLBRAB9A | |
| SCHEMBL5565082 | 0.76 | KDM4E (0.62) | GPR35ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31437284 | 0.76 | KDM4E (0.62) | GPR35ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10954062 | 0.76 | MAOB (0.46) | GPR35ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11638394 | 0.76 | GPR35 (0.70) | GPR35ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126617-A | PROPHYLAXIS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4064248-A | TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-3959289-A | PROPHYLACTICS IN ALLERGIES | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |