Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 10/20 | 0.59 |
| ▸ | CD40 | P25942 | 1/20 | 0.50 |
| ▸ | CD40LG | P29965 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190972 | 1.00 | ENPP2 (0.59) | ENPP2CD40CD40LGAURKAAURKB | |
| SCHEMBL11594349 | 0.82 | ENPP2 (0.85) | ENPP2CD40CD40LGPRMT1APEX1 | |
| SCHEMBL30716918 | 0.82 | ENPP2 (0.85) | ENPP2CD40CD40LGPRMT1APEX1 | |
| SCHEMBL29637807 | 0.82 | ENPP2 (0.85) | ENPP2CD40CD40LGPRMT1APEX1 | |
| SCHEMBL10891071 | 0.82 | ENPP2 (0.85) | ENPP2CD40CD40LGPRMT1APEX1 | |
| SCHEMBL10891093 | 0.82 | ENPP2 (0.85) | ENPP2CD40CD40LGPRMT1APEX1 | |
| SCHEMBL11848060 | 0.81 | APEX1 (0.48) | ENPP2CD40CD40LGPRMT1APEX1 | |
| SCHEMBL11594336 | 0.81 | ENPP2 (0.84) | ENPP2CD40CD40LGPRMT1APEX1 | |
| SCHEMBL11764265 | 0.81 | ENPP2 (0.72) | ENPP2CD40CD40LGPRMT1PRMT3 | |
| SCHEMBL11847968 | 0.76 | APEX1 (0.49) | ENPP2AURKAAURKBAPEX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013470-B1 | RUTIN POLY(H-) SULFATES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1983-05-25 | — | — | EP | disclosed |