Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.72 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | CD40 | P25942 | 1/20 | 0.46 |
| ▸ | CD40LG | P29965 | 1/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637807 | 0.89 | ENPP2 (0.85) | ENPP2PRMT1APEX1CD40CD40LG | |
| SCHEMBL10891093 | 0.89 | ENPP2 (0.85) | ENPP2PRMT1APEX1CD40CD40LG | |
| SCHEMBL10891071 | 0.89 | ENPP2 (0.85) | ENPP2PRMT1APEX1CD40CD40LG | |
| SCHEMBL30716918 | 0.89 | ENPP2 (0.85) | ENPP2PRMT1APEX1CD40CD40LG | |
| SCHEMBL11594349 | 0.89 | ENPP2 (0.85) | ENPP2PRMT1APEX1CD40CD40LG | |
| SCHEMBL11594336 | 0.88 | ENPP2 (0.84) | ENPP2PRMT1APEX1CD40CD40LG | |
| SCHEMBL11760582 | 0.87 | APEX1 (0.61) | ENPP2PRMT1APEX1SUMO2SUMO1 | |
| SCHEMBL11760573 | 0.87 | APEX1 (0.61) | ENPP2PRMT1APEX1SUMO2SUMO1 | |
| SCHEMBL11761475 | 0.86 | ENPP2 (0.52) | ENPP2PRMT1APEX1 | |
| SCHEMBL11758959 | 0.83 | ENPP2 (0.91) | ENPP2PRMT1APEX1CD40CD40LG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049640-A | Substituted bisnaphthylazo diphenyl ureido complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1977-09-20 | — | — | US | disclosed |