Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.68 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protokylol SCHEMBL50567 | 0.87 | ADRB2 (0.76) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| Protokylol SCHEMBL210099 | 0.86 | ADRB2 (0.74) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| Protokylol SCHEMBL523029 | 0.85 | ADRB2 (0.73) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL11180839 | 0.85 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL11180299 | 0.82 | ADRB2 (0.69) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL11670365 | 0.81 | ADRB3 (0.70) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL9360625 | 0.81 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL10446972 | 0.81 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL9361014 | 0.81 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| Oxalic Acid SCHEMBL11187214 | 0.81 | ADRB2 (0.63) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376780-A | Novel phenethylamine derivatives and bronchdilator containing the same | EISAI CO., LTD. (JP) | 1983-03-15 | — | — | US | disclosed |
| US-4317930-A | Phenethylamine derivatives and bronchdilator containing the same | EISAI CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |