Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 14/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446972 | 1.00 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| SCHEMBL9361014 | 1.00 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| Protokylol SCHEMBL50567 | 0.82 | ADRB2 (0.76) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| Protokylol SCHEMBL210099 | 0.81 | ADRB2 (0.74) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| SCHEMBL11191804 | 0.81 | ADRB2 (0.68) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| Protokylol SCHEMBL523029 | 0.80 | ADRB2 (0.73) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| SCHEMBL25858236 | 0.79 | TAAR1 (0.60) | SLC6A4SLC6A3CYP2D6TSHR | |
| SCHEMBL11670365 | 0.78 | ADRB3 (0.70) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| SCHEMBL11810215 | 0.75 | ADRB2 (0.73) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| Arformoterol SCHEMBL3679114 | 0.75 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390762-B1 | New bronchospasmolytic compounds and process for their preparation | DRACO AB (SE) | 1994-01-19 | — | — | EP | claimed |
| EP-0390762-A1 | New bronchospasmolytic compounds and process for their preparation | Aktiebolaget Draco (SE) | 1990-10-03 | — | — | EP | claimed |
| JP-2286650-A | — | — | None | — | — | JP | disclosed |
| EP-0390762-B1 | New bronchospasmolytic compounds and process for their preparation | DRACO AB (SE) | 1994-01-19 | — | — | EP | disclosed |
| JP-H02286650-A | NOVEL ANTIBRONCHOSPASMODIC COMPOUND AND ITS PRODUCTION | DRACO:AB | 1990-11-26 | — | — | JP | disclosed |
| EP-0390762-A1 | New bronchospasmolytic compounds and process for their preparation | Aktiebolaget Draco (SE) | 1990-10-03 | — | — | EP | disclosed |