Prometon

SCHEMBL11191998

CCC(Nc1nc(Cl)nc(NC(CC)OC)n1)OC.COc1nc(NC(C)C)nc(NC(C)C)n1

nearest known ligand 0.54

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	GAA	P10253	3/20	0.54

▸	TDP1	Q9NUW8	1/20	0.54

▸	MEN1	O00255	2/20	0.47

▸	KMT2A	Q03164	2/20	0.47

▸	CYP1A2	P05177	2/20	0.47

▸	SMN1; SMN2	Q16637	2/20	0.40

▸	L3MBTL1	Q9Y468	2/20	0.39

▸	TP53	P04637	1/20	0.38

▸	HTT	P42858	1/20	0.38

▸	POLB	P06746	1/20	0.37

▸	ALDH1A1	P00352	2/20	0.36

▸	CYP2C19	P33261	1/20	0.36

▸	KCNH3	Q9ULD8	1/20	0.35

▸	LMNA	P02545	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10974676	0.93	GAA (0.63)	GAATDP1MEN1KMT2ACYP1A2
SCHEMBL9320202	0.86	GAA (0.50)	GAATDP1MEN1KMT2ACYP1A2
SCHEMBL25083867	0.83	GAA (0.67)	GAATDP1MEN1KMT2ACYP1A2
Prometon SCHEMBL1517242	0.78	KMT2A (0.61)	GAATDP1MEN1KMT2ACYP1A2
SCHEMBL11544671	0.78	CYP1A2 (0.41)	GAATDP1MEN1KMT2ACYP1A2
Prometon SCHEMBL22999	0.78	KMT2A (0.61)	GAATDP1MEN1KMT2ACYP1A2
Prometon SCHEMBL7003877	0.77	GAA (0.58)	GAATDP1MEN1KMT2ACYP1A2
Ametryne SCHEMBL7006285	0.75	HTT (0.48)	GAATDP1MEN1KMT2ACYP1A2
SCHEMBL10713400	0.75	CYP1A2 (0.44)	GAATDP1MEN1KMT2ACYP1A2
SCHEMBL25766191	0.74	KMT2A (0.55)	GAATDP1MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4422868-A	PLANT GROWTH REGULATORS	ROHM AND HAAS COMPANY (US)	1983-12-27	—	—	US	disclosed