Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prometon SCHEMBL9270641 | 0.92 | SMN1; SMN2 (0.53) | GAATDP1SMN1; SMN2TSHRHSD17B10 | |
| Prometon SCHEMBL9738925 | 0.92 | SMN1; SMN2 (0.53) | GAATDP1SMN1; SMN2TSHRHSD17B10 | |
| Ametryne SCHEMBL7006285 | 0.91 | HTT (0.48) | GAATDP1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL25083867 | 0.85 | GAA (0.67) | GAATDP1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11678083 | 0.85 | GAA (0.67) | GAATDP1SMN1; SMN2TSHRHSD17B10 | |
| Terbutryne SCHEMBL9297131 | 0.84 | GAA (0.52) | GAATDP1SMN1; SMN2TSHRHSD17B10 | |
| Prometryn SCHEMBL20723889 | 0.82 | GAA (0.58) | GAATDP1SMN1; SMN2TSHRHSD17B10 | |
| Prometryn SCHEMBL7657627 | 0.80 | MAPK1 (0.56) | GAATDP1SMN1; SMN2TSHRHSD17B10 | |
| Prometon SCHEMBL22999 | 0.80 | KMT2A (0.61) | GAATDP1SMN1; SMN2ALDH1A1MEN1 | |
| Prometon SCHEMBL1517242 | 0.80 | KMT2A (0.61) | GAATDP1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268815-A2 | TRIAZINE DEGRADING ENZYMES | Maxygen, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001064912-A2 | TRIAZINE DEGRADING ENZYMES | MAXYGEN, INC. (US) | 2001-09-07 | — | — | WO | disclosed |