SCHEMBL11544671

SCHEMBL11544671

CCC(Nc1nc(NC(CC)OC)nc(NC(CC)OC)n1)OC

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.34
CYP2C19 P33261 2/20 0.34
TP53 P04637 1/20 0.34
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 2/20 0.31
KCNH3 Q9ULD8 1/20 0.31
F2 P00734 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10974676 0.84 GAA (0.63) CYP1A2MEN1KMT2AL3MBTL1CYP2C19
SCHEMBL11542372 0.82 CYP1A2 (0.38) CYP1A2MEN1KMT2ACYP2C19GAA
Prometon SCHEMBL11191998 0.78 GAA (0.54) CYP1A2MEN1KMT2AL3MBTL1CYP2C19
SCHEMBL11545711 0.74 MEN1 (0.40) CYP1A2MEN1KMT2AL3MBTL1CYP2C19
SCHEMBL7736357 0.71 ALDH1A1 (0.50) MEN1KMT2AL3MBTL1TP53GAA
SCHEMBL6754311 0.70 CYP2D6 (0.35) CYP1A2MEN1KMT2A
SCHEMBL3123080 0.69 GAA (0.39) CYP1A2MEN1KMT2AGAATDP1
SCHEMBL7736360 0.68 TSHR (0.34) CYP1A2KMT2AL3MBTL1CYP2C19TP53
SCHEMBL6081464 0.68 CDK2 (0.40)
SCHEMBL3618634 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4180488-A DISCOLORATION INHIBITION ON BAKING CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1979-12-25 US disclosed