Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570012 | 0.88 | MAOB (0.59) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL8675295 | 0.86 | GLA (0.55) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL11322258 | 0.80 | MAOB (0.61) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL23457949 | 0.80 | GLA (0.57) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL23458032 | 0.80 | GLA (0.57) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL8461885 | 0.79 | TDP1 (0.52) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL8461888 | 0.79 | TDP1 (0.52) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL5599268 | 0.77 | ALDH1A1 (0.59) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL4471707 | 0.77 | MAOB (0.50) | MAOBTDP1GLAALOX15ALDH1A1 | |
| SCHEMBL6518363 | 0.77 | MAOB (0.50) | MAOBTDP1GLAALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071175-A2 | Phenylalkyloxirane-carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-02-09 | — | — | EP | disclosed |