Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458032 | 0.94 | GLA (0.57) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL23457949 | 0.94 | GLA (0.57) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL11192501 | 0.86 | MAOB (0.46) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL18773959 | 0.86 | GLA (0.50) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL8461888 | 0.83 | TDP1 (0.52) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL8461885 | 0.83 | TDP1 (0.52) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL19591781 | 0.82 | GLA (0.46) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL6518363 | 0.82 | MAOB (0.50) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL5599268 | 0.82 | ALDH1A1 (0.59) | GLATDP1MAOBALOX15ALDH1A1 | |
| SCHEMBL4471707 | 0.82 | MAOB (0.50) | GLATDP1MAOBALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760166-A | HAVING AVAILABLE ANHYDRIDE FUNCTIONAL GROUPS CAPABLE OF IMMOBILIZING BIOLOGICAL MOLECULES AND HYDROLYZED ANHYDRIDE FUNCTIONAL GROUPS | BIO MERIEUX (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5489653-A | Water-soluble compounds derived from homopolymer or copolymer of maleic anhydride, and applications of the said compounds to supporting biological molecules | BIO MERIEUX (FR) | 1996-02-06 | — | — | US | disclosed |
| US-5439972-A | Polymaleic anhydrides solubilized by reactions with alkanol amines or alkanol mercaptans, for immobilizing proteins, antibodies, antigens, enzymes or other biological compounds | BIO MERIEUX (FR) | 1995-08-08 | — | — | US | disclosed |