Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.45 |
| ▸ | RELA | Q04206 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11192289 | 0.99 | RAB9A (0.46) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11186212 | 0.95 | RAB9A (0.46) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11195680 | 0.91 | APP (0.46) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11192099 | 0.91 | NPC1 (0.48) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11195163 | 0.90 | APP (0.47) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11198873 | 0.86 | APP (0.48) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11198471 | 0.86 | HDAC6 (0.52) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL8428720 | 0.86 | NPC1 (0.56) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11200139 | 0.81 | APP (0.50) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL10000258 | 0.78 | ATP4A (0.56) | RAB9ANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083204-A2 | 2-Aminophenol derivatives and process for their preparation | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |