Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | DDO | Q99489 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 7/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31381369 | 1.00 | DAO (0.50) | DAODDOPIN1FLT3TSHR | |
| SCHEMBL3838663 | 0.87 | TSHR (0.58) | DAOFLT3TSHRIDO1KDM4E | |
| SCHEMBL5637951 | 0.85 | DAO (0.49) | DAODDOPIN1FLT3TSHR | |
| SCHEMBL5694475 | 0.80 | GPR17 (0.44) | KDM4E | |
| SCHEMBL5694483 | 0.80 | CASP3 (0.54) | KDM4EALDH1A1HPGDAPEX1HSD17B10 | |
| SCHEMBL16240111 | 0.80 | DAO (0.50) | DAODDOPIN1FLT3TSHR | |
| SCHEMBL1122187 | 0.79 | PTGDR2 (0.45) | DAODDOPIN1FLT3PTGDR2 | |
| SCHEMBL5795144 | 0.79 | DAO (0.51) | DAODDOPIN1FLT3IDO1 | |
| SCHEMBL3422658 | 0.78 | PTGDR2 (0.46) | ALDH1A1HPGDPTGDR2NR3C1PGR | |
| SCHEMBL49270 | 0.77 | LOXL2 (0.56) | DAODDOFLT3IDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068563-A2 | Heterocyclic acetic acid compounds and compositions for treating bone diseases | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |