Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.78 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.78 |
| ▸ | HTR1A | P08908 | 1/20 | 0.78 |
| ▸ | PKM | P14618 | 1/20 | 0.78 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.73 |
| ▸ | CNR2 | P34972 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | PTGES | O14684 | 1/20 | 0.68 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.68 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.68 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159263 | 0.90 | PTGS2 (0.80) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| SCHEMBL10735108 | 0.88 | PTGS2 (0.80) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| Acemetacin SCHEMBL23843 | 0.88 | PTGS2 (1.00) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| Acemetacin SCHEMBL29402955 | 0.88 | PTGS2 (1.00) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| SCHEMBL12609003 | 0.88 | PTGS2 (0.85) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| SCHEMBL13800608 | 0.87 | PTGS2 (0.81) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| Acemetacin SCHEMBL10910170 | 0.87 | PTGS2 (0.98) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| Acemetacin SCHEMBL5400266 | 0.87 | PTGS2 (0.98) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| SCHEMBL9654237 | 0.87 | PTGS2 (0.84) | PTGS2PTGS1GLO1HIF1AHTR1A | |
| SCHEMBL4549122 | 0.87 | PTGS2 (1.00) | PTGS2PTGS1GLO1HIF1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58201763-A | — | — | None | — | — | JP | disclosed |
| JP-S58201763-A | INDOLEACETOXYACETIC ACID ESTER | KOWA CO | 1983-11-24 | — | — | JP | disclosed |