Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202057 | 0.88 | KDM4C (0.43) | GPR3KDM4EALDH1A1IDO1GABRP | |
| SCHEMBL11198396 | 0.86 | GPR3 (0.64) | GPR3KDM4EALDH1A1IDO1GABRP | |
| Benzonaphthyridine SCHEMBL30897319 | 0.80 | GPR3 (1.00) | GPR3KDM4EALDH1A1HPGDMAOA | |
| Benzonaphthyridine SCHEMBL29600756 | 0.80 | GPR3 (1.00) | GPR3KDM4EALDH1A1HPGDMAOA | |
| Benzonaphthyridine SCHEMBL51197 | 0.80 | GPR3 (1.00) | GPR3KDM4EALDH1A1HPGDMAOA | |
| SCHEMBL4485428 | 0.74 | GPR3 (0.87) | GPR3KDM4EALDH1A1HPGDMAOA | |
| SCHEMBL29802283 | 0.72 | KDM4E (0.67) | GPR3KDM4EALDH1A1IDO1GABRP | |
| SCHEMBL2407978 | 0.72 | KDM4E (0.67) | GPR3KDM4EALDH1A1IDO1GABRP | |
| SCHEMBL31135312 | 0.72 | KDM4E (0.67) | GPR3KDM4EALDH1A1IDO1GABRP | |
| SCHEMBL2407348 | 0.72 | KDM4E (0.67) | GPR3KDM4EALDH1A1IDO1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369318-A | USING A BENZO-OR PYRIDO-CINNOLINES AS BLEACH CATALYST | CIBA-GEIGY LTD. (CH) | 1983-01-18 | — | — | US | disclosed |
| US-4266011-A | FUSED PYRIDAZINE CATALYST | CIBA-GEIGY AG (CH) | 1981-05-05 | — | — | US | disclosed |
| US-4075074-A | Method for preparing benzo[C]cinnoline and its derivatives | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) | 1978-02-21 | — | — | US | disclosed |