SCHEMBL2407348

SCHEMBL2407348

c1ccc2c(c1)cnc1cnccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.67
GPR3 P46089 1/20 0.67
HTT P42858 2/20 0.49
ALDH1A1 P00352 2/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
CYP3A4 P08684 2/20 0.47
LMNA P02545 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPKAPK2 P49137 1/20 0.46
KDM4A O75164 1/20 0.42
KDM4B O94953 1/20 0.42
KDM5C P41229 1/20 0.42
KDM4C Q9H3R0 1/20 0.42
KDM5B Q9UGL1 1/20 0.42
KDM3A Q9Y4C1 1/20 0.42
PDGFRB P09619 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31135312 1.00 KDM4E (0.67) KDM4EGPR3HTTALDH1A1NCOA1
SCHEMBL8067522 0.85 KDM4E (0.63) KDM4EGPR3HTTALDH1A1NCOA1
SCHEMBL2413552 0.84 KDM4E (0.67) KDM4EGPR3HTTALDH1A1NCOA1
SCHEMBL29802283 0.84 KDM4E (0.67) KDM4EGPR3HTTALDH1A1NCOA1
SCHEMBL2407978 0.84 KDM4E (0.67) KDM4EGPR3HTTALDH1A1NCOA1
Phenanthridine SCHEMBL28242096 0.82 KDM4E (0.69) KDM4EGPR3HTTALDH1A1NCOA1
Phenanthridine SCHEMBL9106884 0.81 GPR3 (1.00) KDM4EGPR3ALDH1A1CYP3A4LMNA
Phenanthridine SCHEMBL30823553 0.81 GPR3 (1.00) KDM4EGPR3ALDH1A1CYP3A4LMNA
Phenanthridine SCHEMBL8666 0.81 GPR3 (1.00) KDM4EGPR3ALDH1A1CYP3A4LMNA
Phenanthridine SCHEMBL30914262 0.81 GPR3 (1.00) KDM4EGPR3ALDH1A1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357188-A1 PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-11-09 US disclosed
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-05-18 US disclosed
US-11066351-B2 Organic compound, three-dimensional organic framework formed by using organic compound, separation sieve and optical layer, which comprise organic framework, and optical device comprising optical layer as optical amplification layer IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2021-07-20 US disclosed
US-10472380-B2 Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof PLACON THERAPEUTICS, INC. (US) 2019-11-12 US disclosed
US-20190031586-A1 ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2019-01-31 US disclosed
US-9947877-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2018-04-17 US disclosed
US-20170349615-A1 PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF XLINK THERAPEUTICS, INC. 2017-12-07 US disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 US disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 US disclosed
US-9771387-B2 Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof PLACON THERAPEUTICS (US) 2017-09-26 US disclosed
US-20160285010-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-09-29 US disclosed
US-20160152646-A1 PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF XLINK THERAPEUTICS, INC. 2016-06-02 US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 US disclosed
WO-2015009841-A2 PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF BLEND THERAPEUTICS (US) 2015-01-22 WO disclosed
US-20140088066-A1 PLATINUM COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER BLEND THERAPEUTICS (US) 2014-03-27 US disclosed
WO-2014043243-A2 PLATINUM COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER BLEND THERAPEUTICS (US) 2014-03-20 WO disclosed
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349615-A1 PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF TP53, PDCD1LG2, IDH1 KDM4E 4074/4885GPR3 2899/4885HTT 353/4885
US-20160152646-A1 PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF TP53, PDCD1LG2, IDH1 KDM4E 4074/4885GPR3 2899/4885HTT 353/4885
US-20140088066-A1 PLATINUM COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER APEX1, DPYD, VHL KDM4E 2370/4885GPR3 3910/4885HTT 189/4885
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION AOC2, AZI2, KCNH2 KDM4E 995/4885GPR3 3295/4885HTT 1809/4885
US-20230357188-A1 PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF AHR, ORAI3, WNT3 KDM4E 3942/4885GPR3 8/4885HTT 613/4885
US-11066351-B2 Organic compound, three-dimensional organic framework formed by using organic compound, separation sieve and optical layer, which comprise organic framework, and optical device comprising optical layer as optical amplification layer OR10J3, POF1B, ORC3 KDM4E 2692/4885GPR3 1337/4885HTT 4000/4885
US-20190031586-A1 ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER OR10J3, POF1B, ORC3 KDM4E 2692/4885GPR3 1337/4885HTT 4000/4885
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, EHD1 KDM4E 2555/4885GPR3 4426/4885HTT 26/4885
US-10472380-B2 Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof TP53, PDCD1LG2, IDH1 KDM4E 4074/4885GPR3 2899/4885HTT 353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.